Endocrine Abstracts

Introduction: Hyperandrogenism is a relatively common medical condition, however severe post-menopausal hyperandrogenism should raise suspicion of a malignant etiology and prompt clinical evaluation. Furthermore, androgen excess has also been associated with severely decreased quality of life. As such, identification of its cause and adequate treatment should not be delayed.Case Report: We report a case of a 66-year-old woman, who had a 5-year history of...

Introduction: Graves Disease (GD) is an autoimmune disease, in which CD4+ Th2 cells secrete interleucin-4 (IL-4) and IL-5 and activate antibody production. IL-4 has been considered a therapeutic target for treatment of immune-related diseases, by enhancing and redirecting T and B cell function. Dupilumab, a monoclonal antibody, inhibits IL-4 and IL-13 and is currently used for treatment of atopic dermatitis, nasal polyposis and asthma. There is a single case report of painless...

Introduction: Thyroid storm, a life-threatening manifestation of hyperthyroidism, presents a complex clinical challenge that demands swift and precise intervention. The heart is one of the most important target organs affected by the thyrotoxic state. Thyrotoxicosis may lead to sinus tachycardia, hypertension, tachycardiomyopathy, atrial fibrillation and heart failure.Case Presentation: A 46-year-old female presented to the emergency department with symp...